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Journal of Medicine and Philosophy 1991 16(6):593-612; doi:10.1093/jmp/16.6.593
© 1991 by Journal of Medicine and Philosophy Inc.
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© 1991 by The Society for Health and Human Values

Human Germ-Line Therapy: The Case for Its Development and Use

Burke K. Zimmerman, Ph.D.

Spectrum International P.O. Box 120, SF-02631 ESPOO, Finland.


   Abstract

The rationale for pursuing the development and use of Germ-Line selection and modification techniques is examined in this essay. The argument is put forth that it is the moral obligation of the medical profession to make available to the public any technology that can cure or prevent pathology leading to death and disability, in both the present and future generations. Society should pursue the development of strategies for preventing or correcting, at the Germ-Line level, genetic features that will lead to, or enhance, pathological conditions. Because prenatal screening and even early embryo screening and selection can prevent only a subset of known genetic disorders, direct genetic intervention is the only way in which certain couples can exercise their rights to reproductive health. Finally, the arguments most often raised against the pursuit of and use of methods for Germ-Line intervention shall be discussed.

Keywords: Germ-Line therapy, pre-implantation embryo screening gamete modification, risk and uncertainty


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